Assistant researcher in experimental cardiovascular research

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Description of the workplace The employment is located in a research group focusing on cardiovascular and neurovascular disease, with particular interest in mechanisms that link vascular dysfunction and sphingolipid signalling to organ damage. The group conducts translational research with experimental disease models and combines functional phenotyping with cellular, histological and molecular methods.

The assistant researcher will contribute to the group's work in experimental cardiovascular research focusing on myocardial infarction and heart failure as well as sphingolipid-related mechanisms. The work is conducted in an international research environment and includes collaboration with other research groups and infrastructures at Lund University.

We offer Lund University is a government authority, which means that you receive special benefits, generous holidays and a favourable occupational pension.

We offer an international and interdisciplinary research environment with access to established experimental models and advanced methods for cardiovascular phenotyping, cellular and molecular analysis and image analysis. The work provides the opportunity to combine several methodological approaches for studying mechanisms behind cardiovascular disease.

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Tasks and responsibilities You will work with experimental research on mechanisms that contribute to the development and progression of cardiovascular disease, with particular focus on myocardial infarction, subsequent cardiac dysfunction and neurocardiovascular regulation.

Your main tasks will be to: Implement and analyze experimental heart attack models in rodents, including surgical ligation of left-front downward coronary artery (LAD) ligation, implement and analyze heart-MR for functional and structural characterization of the heart, analyze sympathetic and vagal decomposition and neural pathways related to cardiovascular function, implement tissue clearance and light-sheet microscopy for three-dimensional visualisation and quantitative analysis of nervous and vascular structures, conduct histological, immunohistochemical and molecular analyses of cardiac and nervous tissue, analyze and interpret data related to sphingolipid metabolism and S1P signalling.

Integrate functional, cellular, histological and molecular data and conduct statistical analysis, document and compile research results and contribute to scientific publications and presentations, collaborate with other members of the research group and external partners.

Qualifications Requirements for the position are: Doctoral degree in biomedicine, medicine, physiology or other relevant field of employment, Documented research experience in experimental cardiovascular research.

Practical experience in experimental models of myocardial infarction and/or cardiac failure in rodents.

Experience of functional phenotyping of the heart, including cardiac MR, Experience of histological and molecular biological analysis of cardiovascular tissue.

Good ability to independently plan, carry out, analyze and document experimental research work, Good ability to communicate scientific results in English in speech and writing, Good ability to collaborate in an interdisciplinary and international research environment.

Merit for employment is: Experience of tissue clearing and light-sheet microscopy, Experience of analysis and visualization of sympathetic and vagal denervervation and nerve pathways, Experience of three-dimensional image analysis and quantitative analysis of microscopic imaging data, Experience of research on sphingolipids, especially S1P signalling, in relation to cardiovascular disease, Experience of analysis of mass spectrometrically generated lipid data, Experience of combining neurobiological, immunological and cardiovascular analyses.

Other Employment is a special fixed-term employment (SÄVA) for 12 months with the scope 80 percent. The desired start date is 2026-11-01 or by agreement.

How to apply The employment is applied for through Lund University's recruitment system. The application shall contain a personal letter stating the interest in the employment and a description of how the applicant's experience corresponds to the tasks and qualification requirements. The application must also include CV, publication list, doctoral degree certificates and contact information for reference persons.

More information about the Faculty of Medicine The Faculty of Medicine is an area of activity within Lund University, with responsibility for education and research in medicine, healthcare and health. The programme is conducted in close collaboration with the health care system and is well rooted in the faculty's strong research tradition. The faculty's research spans a broad field of experimental basic research, patient-related clinical research and health science research. The Faculty of Medicine, with more than 1800 employees and 3000 students in Lund, Malmö and Helsingborg, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

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