Postdoctoral in Structural Bioinformatics

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Description of the workplace

As postdoctoral, you become part of the research group Proteinevolution, led by Gemma C. Atkinson at the Department of Experimental Medical Science, Lund University. We use comparative genomics, sensitive methods for predicting protein function and structural bioinformatics to investigate how microbial conflicts develop and work at the molecular level, especially the interaction between bacteria and bacteriophages. Our calculation-oriented research is closely integrated with experimental work through collaborations in microbiology, biochemistry and structural biology.

Projektbeskrivning

Bacteriophages encode many proteins whose functions and interaction partners are still unknown. In the project, you combine protein structure and complexing with comparative genomics and evolutionary analyzes to investigate interactions between bacteriophage proteins and between phage proteins and their bacterial hosts. The goal is to detect previously unknown molecular interactions and understand how proteins evolution affect their function in phage biology and virus host interactions. The calculation-based predictions give rise to hypotheses that can be investigated experimentally together with our partners.

Tasks and responsibilities

You will conduct calculation-oriented research with Python programming and large-scale prediction of protein structures using high-performance calculation resources. You will work near other members of the research group and external partners. The employment gives you the opportunity to develop your independence as a researcher and broaden your scientific skills. It can also be able to participate in teaching and gain experience of tutoring on master students.

Qualifications

Requirements for the employment are:

• You have a doctoral degree or equivalent foreign degree in bioinformatics, molecular biology, microbiology or a related substance. The doctoral degree must be completed at the latest at the time when employment decisions are made.
• You have good ability to develop and implement high quality research.
• You have good programming skills.
• You have in-depth knowledge of bacteriophage molecular biology.
• You have extensive experience in prediction of protein structures and using such predictions in biological research.
• You have published research on bacteriophages in reputable scientific journals.

Merit for the employment is:

• Mainly, the applicant in question that has graduated a maximum of three years before the last application date.
• You have experience of predicting functions of proteins with unknown function by integrating information about sequence, structure and genomic context.
• You have experience in interdisciplinary research collaborations.
• You have developed bioinformatic open source tools.
• You have good educational ability.

The assessment of the applicants will primarily be based on their scientific qualifications and potential as a researcher. Particular emphasis will be attached to scientific ability in the subject area.

We are offering

We offer an interdisciplinary research environment where bioinformatics, microbiology, biochemistry and structural biology meet to investigate proteins function and evolution. You will cooperate closely with researchers in both computational and experimental research and have access to high performance calculation resources. The employment gives you the opportunity to develop their own research ideas, build international collaborations and gain experience of teaching and supervision.

Lund University is a state authority, which means that you get special benefits, generous holiday and a favorable occupational pension. Read more on the university's website about being employed with us working with us.

If the employment

The employment is a fixed-term employment for two years, 100% with start date 2027-02-01 or as agreed. Employment at Lund University is conducted in Sweden and you will be located at the Biomedical Center (BMC) in Lund and is expected to perform your work on site.

The employment is time-limited to at least two years, max three years according to collective agreement on time-limited employment as postdoctoral (employer). An employment that postdoctoral is intended as an initial step in his career and as an opportunity to further deepen and broaden research competence.

This is how you are looking for

The employment is searched via the university's recruitment system. The application must contain a personal letter where you describe why you are interested in the employment and how it corresponds to your merits. Also attach diplomas and a CV with publication list, links to, for example, code on GitHub and contact information to two reference persons.

More information about the Faculty of Medicine

The Faculty of Medicine is an area of activity within Lund University, with responsibility for education and research in medicine, health and health. The education takes place in close collaboration with health care and is well anchored in the faculty's strong research tradition. The faculty's research spans a wide field in experimental basic research, patient-related clinical research and health science research. The medical faculty, with just over 1800 employees and 3000 students in Lund, Malmö and Helsingborg, is a knowledge-intensive meeting place for students, teachers and researchers from around the world.

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