Research Specialist in medicinal chemistry and drug discovery of small molecules

Do you want to contribute to improving human health?

Department of Clinical Neuroscience (CNS) conducts research and education in the field of neuroscience from the molecular level to the society level. The clinical research and education are conducted in collaboration with other research groups from the Karolinska Institutet, with other universities as well as the Stockholm County Council.

Description of the subject area

The research group of Translational Neuropharmacology combines basic science, clinical neurology and therapeutic innovation to develop the next generation treatments for psychiatric and neurological disorders. Embedded in a multidisciplinary team led by Per Svenningsson, you will work at the interface of computational drug design, medicinal chemistry, pharmacology and clinical neuroscience. This position provides opportunity to develop expertise across full drug discovery pipeline for preclinal candidates toward clinical applications

Your mission

During the appointment, the successful applicant will join a multidisciplinary team of drug discovery and development on novel G protein coupled receptor (GPCR) target for the treatment of neurological disorders such as schizophrenia, Parkinson’s disease. He or she will lead chemistry for lead identification and lead optimization toward clinical candidates. The successful applicant is also expected to contribute to the group's educational environment by mentoring master's students and acting as co-supervisor for doctoral students, thereby gaining experience for future leadership roles.

Eligibility requirements

For employment as Research Specialist at Karolinska Institutet, the eligibility requirements stated in the Guidelines for non-teaching positions at Karolinska Institutet are applied in relation to the established profile of employment.

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having a foreign degree deemed equivalent to a Swedish doctoral degree, the applicant must have demonstrated research expertise as well as have documented postdoctoral research experience.
Extensive experience with medicinal chemistry is required, including experience studies of GPCRs, design of blood brain permeable compounds with in vivo efficacy. Excellent command of English, both written and spoken, is required. Great importance will be placed on the ability to collaborate, initiative, and a strong commitment to the goals of the project. We also attach great importance to personal suitability. 

Assessment criteria

It is particularly meritorious that the applicant has demonstrated

• a strong interest in translational research

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Read more about the research group you will be part of
Read more about the Department of Clinical Neuroscience

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents:  PhD certificate, resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

The application must be submitted through the Varbi recruitment system.

KI applies individual and differentiated salary setting in accordance with our collective agreements RALS and RALS-T. Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all!