Postdoctoral position: assembly and regulation of the C. elegans small RNA amplification machinery

At the University of Vienna, almost 11,000 people work together on the big questions of the future. Approximately 7,700 of them are academic staff members. These are individuals who, with their curiosity and their continuous pursuit of excellence, engage in international cutting-edge research and teaching. With us, you will also find space to unfold your potential. We are looking for a/an ...

Postdoctoral position: assembly and regulation of the C. elegans small RNA amplification machinery 

74 Max Perutz Labs  

Job vacancy starting: 01/01/2027 | Working hours:  40.00  | Classification CBA: §48 VwGr. B1 lit. b (postdoc) 

Limited contract until: 

Job ID: 6299

The Max Perutz Labs is a joint research institute of the University of Vienna and the Medical University of Vienna. It was founded in 2005 to deepen the collaboration between the two universities in the field of molecular biosciences. Approximately 450 scientists from over 40 nations work in 40 research groups at the institute, investigating fundamental questions in molecular and cell biology. State-of-the-art research infrastructure supports their work in basic biomedical research.

Explore and teach at the University of Vienna, where over 7,700 brilliant minds have found a unique balance of freedom and support. Join us if you’re passionate about groundbreaking international research and academic excellence. Ready to be part of our team? Let’s shape the future together!

Your personal sphere of play:

The Falk Lab studies how C. elegans amplifies small RNAs to regulate gene expression and protect the genome. This project combines biochemistry, biophysics, and worm genetics to dissect how this machinery functions both in vitro and in the animal. This position is limited for a period of 3 years with the option of extension. 

Your future tasks:

You actively participate in research, teaching, and administration, which means:

•    Drive your research project on the assembly and regulation of the small RNA amplification machinery, bridging in vitro reconstitution and biochemistry with C. elegans genetics.
•    Meet and consult with your supervisor regularly to prioritize your tasks.
•    Participate in group, campus, and workshop activities.
•    Present at conferences and publish results in peer-reviewed journals.
•    Actively seek support through workshops, training, and coaching when useful.
•    Contribute to the education and supervision of Bachelor, Master, and PhD students.

This is part of your personality: 

Required:

•    A PhD, completed or near completion, in biochemistry, molecular biology, structural biology, or a related field.
•    Extensive experience with recombinant protein production and purification.
•    Extensive experience with biophysical methods to assess oligomeric state, ligand binding, and mono- or polydispersity, for example SEC-MALS, mass photometry, ITC, MST, or fluorescence anisotropy.
•    Extensive experience establishing enzymatic activity assays.
•    Good written and spoken English and clear communication.
•    The ability to work independently and as part of a team and to drive a project.

Advantageous:

•    Experience working with C. elegans, including generation of transgenic animals, cytology, and phenotypic assessment.
•    Familiarity with structural biology, cryo-EM or crystallography, or interest in integrating structural data.
•    Experience with microscopy and computational image analysis 

General expectations:

•    Present your work regularly and contribute to manuscripts and, where relevant, grant applications.
•    Keep rigorous, well-documented, and reproducible records and data.
•    Contribute to a collaborative and supportive lab environment.

What we offer:

Work-life balance: Our employees enjoy flexible working hours, remote/hybrid and/or part-time work (upon agreement).

Inspiring working atmosphere: You are a part of an international academic team in a healthy and fair working environment.

Good public transport connections: Your workplace in the center of beautiful Vienna is easily accessible by public transport.

Internal further training & Coaching: Opportunity to deepen your skills on an ongoing basis. There are over 600 courses to choose from – free of charge.

Fixed-term contract and fair salary: The basic salary of EUR 5.079,50;  (14 times a year) increases if we can credit professional experience. This position is limited for a period of 3 years with the option of extension. 

Get off to a great start in your new job: the  Welcome Compass helps you settle into your new role at the University of Vienna and life in Vienna.

Equal opportunities for all: We welcome every additional/new personality to the team!

It is that easy to apply:

• With your scientific curriculum vitae / letter of intent
• With your list of publications
• With your summary of research interests (max. 1 p.)
• Doctoral Degree 
• Contact details of persons who could provide reference letters
• Via our job portal/ Apply now -  button

If you have any questions, please contact:

Sebastian Falk  

sebastian.falk@univie.ac.at

We look forward to new personalities in our team! 
The University of Vienna has an anti-discriminatory employment policy and attaches great importance to equal opportunities, the advancement of women and diversity. We place particular emphasis on enhancing women’s representation among the academic and general university staff, particularly in leadership roles, and therefore expressly encourage qualified women to apply. Given equal qualifications, preference will be given to female candidates.

University of Vienna. Space for personalities. Since 1365.

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​Application deadline: 10/18/2026 

Post Doc