PhD in Protein Design

Projektbeskrivning

Forskarutbildningsämne:Biotechnology

At the Department of Protein Science, we develop predictable and robust techniques for production, purification and detection of proteins. As building blocks for new molecular features, we use small, structurally well-characterized protein domains. The doctoral project is based on our newly developed calcium-regulated affinity proteins (Caras), which binds to its target proteins in the presence of calcium and releases them at low calcium concentrations. By combining proteinengineering with biophysical characterization, structural biology, calculation modeling and machine learning, you will examine how the amino acid sequence and the surroundings ratios control this behavior. The project unites the expertise that has been developed in Professor Sophia Hober's research group at the Royal Institute of Technology (KTH) and Professor Andreas Hougaard Laustsen research group at Denmark Technical University (DTU). The goal is to clarify the principles behind environmentally regulated protein function and translate them into design principles to develop a new generation smarter and more precise therapeutic proteins.

Tutorial:Sophia Hober is proposed to supervise the doctoral student. Decisions are taken on admission

Eligibility for admission

To be admitted to postgraduate education (Cape 7 39 § The Higher Education Ordinance), the applicant is required to have basic eligibility:

• disposed a degree at advanced level, or
• Fulfilled course claims on at least 240 High school credits, at least 60 High school credits at advanced level, or
• In any other way within or outside the country, equivalent knowledge is mainly acquired.

In addition to the above there is also a mandatory requirement in English corresponding to English B / 6.

Selection

To succeed with your doctoral studies on KTH, you need to be targeted and persistent in your work. In selecting the applicants, the ability is assessed to:

• independently pursue his work ahead,
• able to cooperate with others,
• have a professional approach and
• Analyze and work with complex issues.
• Merit is to have documented experience of protein characterization.
• The person we seek will be structured and quality conscious.
• Being able to write and speak fluent English when it is required in the daily work.

After the eligibility requirements, great emphasis will be added to personal qualities.

Target degree: Doctoral degree

Information about admission and employment

Only the one who has been adopted to postgraduate education may be employed as a doctoral student. The total employment period may not be longer than that corresponds to education at full-time postgraduate for four years. An employee doctoral student can to a limited extent (at most 20 %) perform certain tasks within eg. education and administration. A new employment as a doctoral student applies for a maximum of one year, the employment may then be renewed by a maximum of two years at a time. In studies to be terminated with a licentiate degree, the total employment time may not be longer than that corresponds to training at a full-time postgraduate for two years.

As a doctoral student, you get part of KTH's employment benefits and has a monthly salary according to KTH's doctoral salary agreement. Read more about research studies at KTH | KTH | Sweden.

Union representatives

Contact information to union representatives.

Doctoral Section (Technical College Student Union)

Contact information to doktorandsektionen.

Application

You apply via KTH's recruitment system. You as applicants have the main responsibility for your application complete when submitted.

The application must have the following content

• Copies of diplomas and grades from previous university studies and certificates of language requirements (see above). Translations into English or Swedish if the original document is not issued in one of these languages. Copies of original should be renamed
• CV with relevant professional experiences and knowledge.
• Application letter with a brief account of why you want to pursue research studies, about your academic interests and how they relate to your previous studies and future goals. (Max 2 pages)
• Representative publications or technical reports. For longer documents, please attach a summary (Abstract) and a web link to the full text

The application must be received by KTH no later than the last application date at midnight, CET / CEST (Central European Time / Central European Summer Time).

Other

For information on the processing of personal data in connection with recruitment.

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