researchJobsDoctoral student in Biotechnology
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Projektbeskrivning
Forskarutbildningsämne:Biotechnology
At the Department of Protein Science, we develop predictable and robust techniques for production, purification and detection of proteins. As building blocks for new molecular features, we use small, structurally well-characterized protein domains. The doctoral project is based on our newly developed calcium-regulated affinity proteins (Caras), which binds to its target proteins in the presence of calcium and releases them at low calcium concentrations. By combining proteinengineering with biophysical characterization, structural biology, calculation modeling and machine learning, you will examine how the amino acid sequence and the surroundings ratios control this behavior. The project unites the expertise that has been developed in Professor Sophia Hober's research group at the Royal Institute of Technology (KTH) and Professor Andreas Hougaard Laustsen research group at Denmark Technical University (DTU). The goal is to clarify the principles behind environmentally regulated protein function and translate them into design principles to develop a new generation smarter and more precise therapeutic proteins.
Tutorial:Sophia Hober is proposed to supervise the doctoral student. Decisions are taken on admission
Eligibility for admission
To be admitted to postgraduate education (Cape 7 39 § The Higher Education Ordinance), the applicant is required to have basic eligibility:
- disposed a degree at advanced level, or
- Fulfilled course claims on at least 240 High school credits, at least 60 High school credits at advanced level, or
- In any other way within or outside the country, equivalent knowledge is mainly acquired.
In addition to the above there is also a mandatory requirement in English corresponding to English B / 6.
Selection
To succeed with your doctoral studies on KTH, you need to be targeted and persistent in your work. In selecting the applicants, the ability is assessed to:
- independently pursue his work ahead,
- able to cooperate with others,
- have a professional approach and
- Analyze and work with complex issues.
- Merit is to have documented experience of protein characterization.
- The person we seek will be structured and quality conscious.
- Being able to write and speak fluent English when it is required in the daily work.
After the eligibility requirements, great emphasis will be added to personal qualities.
Target degree: Doctoral degree
Information about admission and employment
Only the one who has been adopted to postgraduate education may be employed as a doctoral student. The total employment period may not be longer than that corresponds to education at full-time postgraduate for four years. An employee doctoral student can to a limited extent (at most 20 %) perform certain tasks within eg. education and administration. A new employment as a doctoral student applies for a maximum of one year, the employment may then be renewed by a maximum of two years at a time. In studies to be terminated with a licentiate degree, the total employment time may not be longer than that corresponds to training at a full-time postgraduate for two years.
As a doctoral student, you get part of KTH's employment benefits and has a monthly salary according to KTH's doctoral salary agreement. Read more about research studies at KTH | KTH | Sweden.
Union representatives
Contact information to union representatives.
Doctoral Section (Technical College Student Union)
Contact information to doktorandsektionen.
Application
You apply via KTH's recruitment system. You as applicants have the main responsibility for your application complete when submitted.
The application must have the following content
- Copies of diplomas and grades from previous university studies and certificates of language requirements (see above). Translations into English or Swedish if the original document is not issued in one of these languages. Copies of original should be renamed
- CV with relevant professional experiences and knowledge.
- Application letter with a brief account of why you want to pursue research studies, about your academic interests and how they relate to your previous studies and future goals. (Max 2 pages)
- Representative publications or technical reports. For longer documents, please attach a summary (Abstract) and a web link to the full text
The application must be received by KTH no later than the last application date at midnight, CET / CEST (Central European Time / Central European Summer Time).
Other
For information on the processing of personal data in connection with recruitment.
It may occur that an employment of KTH is located in a safety class. If this is the case for this particular employment, a security review of applicants is made in accordance with the security law (2018: 585) after consent. In these cases, a prerequisite for employment is that applicants will be approved after security testing.
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Project description
Third-cycle subject: Biotechnology
At the Department of Protein Technology, we develop predictable and robust technologies for protein production, purification, and detection using small, structurally well-characterized protein domains as building blocks for new molecular functions. This PhD project builds on our recently developed calcium-regulated affinity binders (CaRAs), which bind their targets in the presence of calcium and release them at low calcium concentrations. By combining protein and protein engineering with biophysical characterization, structural biology, computational modelling, and machine learning, you will investigate how amino acid sequence and environmental conditions govern this behaviour. The project brings together the expertise built in Professor Sophia Hober´s group at KTH Royal Institute of Technology and Professor Andreas Hougaard Laustsen’s gruop at the Technical University of Denmark. The project aims to uncover the principles governing environmentally regulated protein function and translate them into design rules for a new generation of smarter and more precise therapeutic proteins.
Supervision: Sophia Hober is proposed to supervise the doctoral student. Decisions are made on admission
Admission requirements
To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:
- passed a second cycle degree (for example a master's degree), or
- completed course requirements of at least 240 higher education credits, of which at least 60 second-cycle higher education credits, or
- acquired, in some other way within or outside the country, substantially equivalent knowledge
In addition to the above, there is also a mandatory requirement for English equivalent to English B/6.
Selection
In order to succeed as a doctoral student at KTH you need to be goal oriented and persevering in your work. During the selection process, candidates will be assessed upon their ability to:
- independently pursue his or her work
- collaborate with others,
- have a professional approach and
- analyze and work with complex issues.
- Experience with protein production in protein engineering is a merit.
- The ideal candidate should be organized and quality conscious.
- Fluent in English as this will be required in day-to-day work.
After the qualification requirements, great emphasis will be placed on personal skills.
Target degree: Doctoral degree
Information regarding admission and employment
Only those admitted to postgraduate education may be employed as a doctoral student. The total length of employment may not be longer than what corresponds to full-time doctoral education in four years' time. An employed doctoral student can, to a limited extent (maximum 20%), perform certain tasks within their role, e.g. training and administration. A new position as a doctoral student is for a maximum of one year, and then the employment may be renewed for a maximum of two years at a time. In the case of studies that are to be completed with a licentiate degree, the total period of employment may not be longer than what corresponds to full-time doctoral education for two years.
As a doctoral student, you are entitled to a workplace with many employee benefits and monthly salary according to KTH’s Doctoral student salary agreement. Read more about Doctoral studies (PhD) | KTH | Sweden.
Union representatives
Contact information for union representatives.
Doctoral Student’s network (Students’ union on KTH Royal Institute of Technology)
Contact information for PhD chapter.
To apply for the position
Apply for the position and admission through KTH's recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.
Applications must include the following elements:
- Copies of diplomas and grades from previous university studies and certificates of fulfilled language requirements (see above). Translations into English or Swedish if the original document is not issued in one of these languages.Copies of originals must be certified.
- CV including your relevant professional experience and knowledge.
- Application letter with a brief description of why you want to pursue research studies, about what your academic interests are and how they relate to your previous studies and future goals. (Maximum 2 pages long)
- Representative publications or technical reports. For longer documents, please provide a summary (abstract) and a web link to the full text.
Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/Central European Summer Time).
Other information
For information about processing of personal data in the recruitment process.
It may be the case that a position at KTH is classified as a security-sensitive role in accordance with the Protective Security Act (2018:585). If this applies to the specific position, a security clearance will be conducted for the applicant in accordance with the same law with the applicant's consent. In such cases, a prerequisite for employment is that the applicant is approved following the security clearance.
We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.
Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.
Advertisement text from Varbi (the institution's own recruitment system), no licence stated; reproduced with attribution.
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